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CyFlow™ CD41 PE

CyFlow™ CD41 PE
Antigen: CD41
Alternative Name: gpIIb
Clone: MWReg30
Application: Flow cytometry
Format/Fluorochrome: PE
Laser: Blue, Green, Yellow
Target Species: Mouse
Field of Interest: Immunophenotyping, MHC
Species of Origin: Rat
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Isotype: IgG1
Order number: BQ684614

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

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*1 Offer valid until 31/10/2017
Concentration Unit mg/mL Concentration 0.5 Quantity 0.1 mg Volume 0.2... more
CyFlow™ CD41 PE
Concentration Unitmg/mL
Concentration0.5
Quantity0.1 mg
Volume0.2
ImmunogenMouse platelets
Background InformationCD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Specific References

| Sullivan BP, Wang R, Tawfik O, Luyendyk JP: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol·Sci. 2010·May; 115(1):286‑94. <·PMID:·20133375·> | Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C: Integrin αIIb (CD4{01} plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol·Open. 2013·Apr·11; 2(5):525‑32. <·PMID:·23789102·> | Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M: A vasculo‑protective circuit centered on lipoxin A4 and aspirin‑triggered 15‑epi‑lipoxin A4 operative in murine microcirculation. Blood. 2013·Jul·25; 122(4):608‑17. <·PMID:·23733341·> | Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX: Stress‑induced hematopoietic failure in the absence of immediate early response gene X‑1. Haematologica. 2013·Sep·20; <·PMID:·23812939·>