CyFlow™ CD1a APC
| Antigen: | CD1a |
| Alternative Name: | CD1, HTA1, R4 |
| Clone: | SK9 |
| Application: | Flow cytometry |
| Format/Fluorochrome: | APC |
| Laser: | Red |
| Target Species: | Human |
| Field of Interest: | Immunophenotyping |
| Species of Origin: | Mouse |
| Regulatory Status: | RUO |
| Clonality: | monoclonal |
| Emission Maximum: | 660 nm |
| Excitation Maximum: | 650 nm |
| Isotype: | IgG2b |
| HLDA Workshop | HLDA II |
| Quantity | 100 tests |
| Volume | 1 |
| Immunogen | Human thymocytes |
| Background Information | CD1a, together with CD1b and CD1c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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