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CyFlow™ CD41 PE-Cy5

CyFlow™ CD41 PE-Cy5
Antigen: CD41
Alternative Name: gpIIb
Clone: MEM-06
Application: Flow cytometry
Format/Fluorochrome: PE-Cy5
Laser: Blue, Green, Yellow
Target Species: Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 670 nm
Excitation Maximum: 496 nm, 565 nm
Isotype: IgG1
Order number: CW776518

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Quantity 100 tests Volume 0.4 ml Immunogen Leukocytes of a patient suffering from... more
CyFlow™ CD41 PE-Cy5
Quantity100 tests
Volume0.4 ml
ImmunogenLeukocytes of a patient suffering from LGL-type Leukemia
SpecifityThe mouse monoclonal antibody MEM-06 recognizes CD41 antigen, a transmembrane glycoprotein (integrin family) composed of two chains GPIIb α (heavy chain; 120 kDa) and GPIIb β (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Background InformationCD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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