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CyFlow™ Ki-67 Purified

CyFlow™ Ki-67 Purified
Application: Flow cytometry, Immunocytochemistry, Immunohistochemistry, Western blot
Clonality: monoclonal
Target Species: Cow, Human
Regulatory Status: RUO
Source Species: Mouse
Format/Fluorochrome: Purified
Isotype: IgG1
Field of Interest: Transcription
Antigen: Ki-67
Clone: Ki-67
Order number: CR920490
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ Ki-67 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenNuclei of the Hodgkin lymphoma cell line L428
Background InformationKi-67 is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa), both of which are identified by the antibody clone Ki-67. The Ki-67 antigen is essential for cell proliferation and its expression is restricted to the cycling cells. It is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes. Ki-67 thus represents an important tool for detection of proliferating cells, which is of great importance in tumor diagnostics and is commonly used as a prognostic factor in cancer studies.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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