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CyFlow™ ABRA1 Purified
Application: | Flow cytometry, Immunoprecipitation, Western blot |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Source Species: | Mouse |
Format/Fluorochrome: | Purified |
Isotype: | IgG |
Antigen: | ABRA1 |
Clone: | ABRA1-01 |
Field of Interest: | Adaptor proteins, Transcription |
Order number: | AP667270 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ ABRA1 Purified"
Concentration Unit | mg/mL |
Concentration | 1 |
Quantity | 0.1 mg |
Volume | 0.1 mL |
Immunogen | Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag |
Background Information | ABRA1 (Abraxas, CCDC98) is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation. |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Technical Data Sheet
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