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CyFlow™ CD45R APC

CyFlow™ CD45R APC
Antigen: CD45R
Clone: RA3-6B2
Application: Flow cytometry
Format/Fluorochrome: APC
Laser: Red
Target Species: Cat, Human, Mouse
Field of Interest: Immunophenotyping, Phosphorylation
Species of Origin: Rat
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 660 nm
Excitation Maximum: 650 nm
Isotype: IgG2a
Order number: BJ993887

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 0.5 mg/ml Quantity 0.1 mg Volume 0.2 ml Immunogen Abelson murine... more
CyFlow™ CD45R APC
Concentration0.5 mg/ml
Quantity0.1 mg
Volume0.2 ml
ImmunogenAbelson murine leukemia virus-induced pre-B tumor cells
SpecifityThe rat monoclonal antibody RA3-6B2 recognizes an epitope on CD45R antigen, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state.
Background InformationCD45R (B220) is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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