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CyFlow™ CD11c PE-Cy7

CyFlow™ CD11c PE-Cy7
Antigen: CD11c
Alternative Name: p150
Clone: BU15
Application: Flow cytometry
Format/Fluorochrome: PE-Cy7
Laser: Blue, Green, Yellow
Target Species: Human, Non-Human Primates
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 785 nm
Excitation Maximum: 496 nm, 565 nm
Isotype: IgG1
Order number: AL905427

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Quantity 100 tests Volume 0.4 ml Immunogen Dendritic cells of synovial fluid... more
CyFlow™ CD11c PE-Cy7
Quantity100 tests
Volume0.4 ml
ImmunogenDendritic cells of synovial fluid
SpecifityThe mouse monoclonal antibody BU15 reacts with CD11c antigen, a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Background InformationCD11c (αX integrin subunit) forms complex with CD18 (β2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other β2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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